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KMID : 0882419930450040538
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Korean Journal of Medicine
1993 Volume.45 No. 4 p.538 ~ p.542
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A Case of Pseudomelanosis Duodeni Associate with Chronic Renal Failure
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박진호
장병익/강승호/김태년/정문관/이현우/남혜주
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Abstract
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seudomelanosis duodeni is a rare condition that has been only recently recognized.Dark pigment accumulates in macrophages located in the lamina propria of the duodenal mucosa. Diffuse small discreted brownishblack pigmentation at duodenal bulb
was
noted during gastroduodenoscopy by chance, in a 50 year old male patient with chronic renal failure, who
had been treated antihypertensive drugs for 15 years and regular hemodialysis for 6 years.
With the electron microscope, blackish electron dense granules were found within the
cytoplasm of the macrophage located in the lamina propria and with the study
of histochemistry (stained with Prussian-Blue, Masson-Fontana method) the pigment
contained iron and other unknown material.
The source of the pigment or the mrchanism of pigment formation is unclear and has yet
to be clarified.
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KEYWORD
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